The effect of vitamin D and/or Calcium supplementation on periodontitis, Mariana R. Tomaz, Melahat S. Macit, Maria I. Niza, Charlotte A. Jeavons, Berit L. Heitmann and Amanda R. A. Adegboye
Mariana R. Tomaz
Department of Life Sciences Human Food, Nutrition and Public Health Division, Faculty of Science and Technology, University of Westminster, London, UK
Melahat S. Macit
Department of Nutrition and Dietetics, Faculty of Health Sciences, Ondokuz Mayıs University, Samsun, Turkey
Maria I. Niza
Department of Life Sciences Human Food, Nutrition and Public Health Division, Faculty of Science and Technology, University of Westminster, London, UK
Charlotte A. Jeavons
School of Human Sciences, Faculty of Education, Health and Human Sciences, University of Greenwich, London, UK
Berit L. Heitmann
Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark Department of Public Health, Section for General Practice University of Copenhagen, Copenhagen, Denmark
Amanda R Amorim Adegboye (Corresponding author)
School of Human Sciences, Faculty of Education, Health and Human Sciences, University of Greenwich, London, UK
Email: A. Adegboye@greenwich.ac.uk
Objective: To perform a systematic review and assess whether the use of vitamin D and calcium supplements can benefit the prevention of periodontitis and tooth loss among adults and elderly.
Method: Research of MEDLINE, LILACS, Cochrane Library, Scopus and ClinicalTrials.gov and reference lists of relevant papers to identify experimental and observational studies on the effect of vitamin D and/or calcium supplementation on clinical parameters of periodontitis. Primary outcomes were clinical attachment loss (CAL), probing depth (PD) and tooth loss.
Results: Four studies were included. Meta-analysis across studies showed a standardized mean difference (SMD) of –0.194 (95% CI: –0.777 to 0.389) and –0.168 (95% CI: –0.736 to 0.400) for CAL and PD, respectively.
Conclusion: Vitamin D and calcium supplementation seem to have some benefi cialeffect on clinical parameters of periodontitis as a complementary therapy. However, these findings need to be confi rmed before being used in clinical practice.
Keywords: supplementation; calcium; vitamin D; periodontitis
DOI: https://doi.org/10.47556/J.IJFNPH.11.1.2019.4
